Eastern Vascular Society
EVS Main Site Meeting Home Final Program Past & Future Meetings

Back to 2017 ePoster Competition


Outcomes of Resection for Renal Cell Carcinoma with Extensive Inferior Vena Cava Thrombus
Hallie E. Baer, MD, Georges M. Haidar, MD, Taylor D. Hicks, MD, Ronald Rodriguez, MD, PhD, Dharam Kaushik, MD, Maureen K. Sheehan, MD, Matthew J. Sideman, MD, Lori L. Pounds, MD, Mark G. Davies, MD, PhD, MBA.
University of Texas Health San Antonio, San Antonio, TX, USA.

Objective(s): Renal cell carcinoma has a propensity for vascular invasion with tumor thrombus occurring in 10-25% cases. Tumor thrombus invades along the renal vein (level 0) to the IVC (level 1-2) and above the hepatic veins (level 3) until ultimately an atrial thrombus (level 4). Radical nephrectomy and caval thrombectomy represent the only method of local disease and durable oncologic control. The aim of this study is to examine outcomes of resection in the setting of a multidisciplinary team.
Methods: A review of a prospectively maintained database of patients with renal cell carcinoma with tumor thrombus was performed. Patients were evaluated pre-operatively with a standardized protocol to assess for extent of disease, specifically presence (and level) of tumor thrombus using renal protocol CT or MRI. A multidisciplinary surgical approach involving Urology, Cardiothoracic, and Vascular surgery was utilized. Intraoperative Doppler ultrasound and trans-esophageal echocardiography were performed to aid in confirming the level of thrombus and to identify the lumbar and hepatic veins insertion into the vena cava.
Results: A total of 57 patients underwent radical nephrectomy with tumor thrombectomy over the course of 28 months. Patients were predominantly Hispanic (61%) and male (63%) with a history of hypertension (68%), tobacco use (56%), and diabetes (40%). Thrombus level for L0, L1, L2, L3, and L4 disease was 23%, 11%, 32%, 25%, and 11%, respectively. Bypass was required in 35% of cases (veno-veno 25%, cardiopulmonary 11%) and IVC reconstruction with patch only occurred twice (3. 5%). Median length of stay was 12 days with a 30-day re-admission rate of 17. 5%. Mortality at 30 and 90 days for all patients was 5. 7% and 9. 4%, respectively.
Conclusions: Renal cell carcinoma with extensive inferior vena caval thrombus remains a high risk surgery that requires a multidisciplinary surgical approach, but is associated with acceptable mortality and morbidity. Our results demonstrate Hispanic patients present with less invasive disease than non-Hispanics based on level of thrombus, however Hispanic patients have a higher overall mortality at both 30 and 90 days than Non-Hispanic patients. Furthermore, primary vena caval closure is associated with effective caval preservation without associated morbidity.


Back to 2017 ePoster Competition


Hotel Exterior Dining by water Horses Pool